Golgin-45

BLZF1
Identifiers
Aliases	BLZF1, GOLGIN-45, JEM-1, JEM-1s, JEM1, basic leucine zipper nuclear factor 1
External IDs	OMIM: 608692; MGI: 1201607; HomoloGene: 31187; GeneCards: BLZF1; OMA:BLZF1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	169,396,540 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	164,135,058 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; gonad; ; buccal mucosa cell; ; epithelium of colon; ; oral cavity; ; mucosa of esophagus; ; gallbladder; ; rectum; ; superficial temporal artery; ; islet of Langerhans;
	Top expressed in
	lumbar spinal ganglion; ; zygote; ; secondary oocyte; ; esophagus; ; genital tubercle; ; muscle of thigh; ; cardiac muscle tissue of left ventricle; ; neural layer of retina; ; tail of embryo; ; spermatid;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; enzyme binding; DNA binding; protein binding; ubiquitin protein ligase binding;
Cellular component	cytoplasm; Golgi lumen; nucleus; Golgi apparatus; Golgi membrane; membrane; nucleoplasm;
Biological process	regulation of transcription by RNA polymerase II; Golgi to plasma membrane protein transport; protein transport; cell population proliferation; Golgi organization; regulation of cell growth; vesicle-mediated transport; regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	8548
	66352
	ENSG00000117475
	ENSMUSG00000026577
	Q9H2G9; Q5T532
	Q8R2X8
	NM_003666; NM_001320972; NM_001320973
	NM_001160208; NM_001160209; NM_025505; NM_001357052
	NP_001307901; NP_001307902; NP_003657
	NP_001153680; NP_001153681; NP_079781; NP_001343981
	Wikidata
View/Edit Human	View/Edit Mouse

Golgin-45 is a protein that in humans is encoded by the BLZF1 gene.^[5]^[6]

Interactions

Golgin-45 has been shown to interact with GORASP2.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000117475 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026577 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Duprez E, Tong JH, Dérré J, Chen SJ, Berger R, Chen Z, Lanotte M (May 1997). "JEM-1, a novel gene encoding a leucine-zipper nuclear factor upregulated during retinoid-induced maturation of NB4 promyelocytic leukaemia". Oncogene. 14 (13): 1563–70. doi:10.1038/sj.onc.1200995. PMID 9129147.
^ "Entrez Gene: BLZF1 basic leucine zipper nuclear factor 1 (JEM-1)".
^ Barr FA, Preisinger C, Kopajtich R, Körner R (Dec 2001). "Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus". J. Cell Biol. 155 (6): 885–91. doi:10.1083/jcb.200108102. PMC 2150891. PMID 11739402.

External links

BLZF1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Human BLZF1 genome location and BLZF1 gene details page in the UCSC Genome Browser.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000117475 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026577 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9129147-5] Duprez E, Tong JH, Dérré J, Chen SJ, Berger R, Chen Z, Lanotte M (May 1997). "JEM-1, a novel gene encoding a leucine-zipper nuclear factor upregulated during retinoid-induced maturation of NB4 promyelocytic leukaemia". Oncogene. 14 (13): 1563–70. doi:10.1038/sj.onc.1200995. PMID 9129147.

[entrez-6] "Entrez Gene: BLZF1 basic leucine zipper nuclear factor 1 (JEM-1)".

[pmid11739402-7] Barr FA, Preisinger C, Kopajtich R, Körner R (Dec 2001). "Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus". J. Cell Biol. 155 (6): 885–91. doi:10.1083/jcb.200108102. PMC 2150891. PMID 11739402.

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Interactions

References

Further reading

External links