CCAAT/enhancer binding protein zeta

CEBPZ
Identifiers
Aliases	CEBPZ, CBF, CBF2, HSP-CBF, NOC1, CCAAT/enhancer binding protein zeta, CCAAT enhancer binding protein zeta
External IDs	OMIM: 612828; MGI: 109386; HomoloGene: 4210; GeneCards: CEBPZ; OMA:CEBPZ - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	37,231,596 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	79,244,495 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; tendon of biceps brachii; ; ventricular zone; ; internal globus pallidus; ; left testis; ; gastrocnemius muscle; ; right testis; ; testicle; ; epithelium of colon; ; pericardium;
	Top expressed in
	otic placode; ; basilar part of occipital bone; ; saccule; ; otic vesicle; ; tail of embryo; ; genital tubercle; ; maxillary prominence; ; lacrimal gland; ; mandibular prominence; ; Ileal epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	regulation of transcription, DNA-templated; transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; ribosome biogenesis;
	Sources:Amigo / QuickGO
Orthologs
	10153
	12607
	ENSG00000115816
	ENSMUSG00000024081
	Q03701
	P53569
	NM_005760
	NM_001024806; NM_009882
	NP_005751
	NP_001019977
	Wikidata
View/Edit Human	View/Edit Mouse

CCAAT/enhancer-binding protein zeta is a protein that in humans is encoded by the CEBPZ gene.^[5]^[6]^[7]

Interactions

CCAAT/enhancer binding protein zeta has been shown to interact with:

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000115816 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024081 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lum LS, Sultzman LA, Kaufman RJ, Linzer DI, Wu BJ (Jan 1991). "A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter". Mol Cell Biol. 10 (12): 6709–17. doi:10.1128/mcb.10.12.6709. PMC 362949. PMID 2247079.
^ ^a ^b Uramoto H, Izumi H, Nagatani G, Ohmori H, Nagasue N, Ise T, Yoshida T, Yasumoto K, Kohno K (Apr 2003). "Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression". Biochem J. 371 (Pt 2): 301–10. doi:10.1042/BJ20021646. PMC 1223307. PMID 12534345.
^ "Entrez Gene: CEBPZ CCAAT/enhancer binding protein zeta".
^ Imbriano C, Bolognese F, Gurtner A, Piaggio G, Mantovani R (Jul 2001). "HSP-CBF is an NF-Y-dependent coactivator of the heat shock promoters CCAAT boxes". J. Biol. Chem. 276 (28): 26332–9. doi:10.1074/jbc.M101553200. hdl:11380/303761. PMID 11306579.
^ Uramoto H, Izumi H, Nagatani G, Ohmori H, Nagasue N, Ise T, Yoshida T, Yasumoto K, Kohno K (Apr 2003). "Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression". Biochem. J. 371 (Pt 2): 301–10. doi:10.1042/BJ20021646. PMC 1223307. PMID 12534345.

External links

CEBPz+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
CEBPZ human gene location in the UCSC Genome Browser.
CEBPZ human gene details in the UCSC Genome Browser.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000115816 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024081 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2247079-5] Lum LS, Sultzman LA, Kaufman RJ, Linzer DI, Wu BJ (Jan 1991). "A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter". Mol Cell Biol. 10 (12): 6709–17. doi:10.1128/mcb.10.12.6709. PMC 362949. PMID 2247079.

[pmid12534345-6] Uramoto H, Izumi H, Nagatani G, Ohmori H, Nagasue N, Ise T, Yoshida T, Yasumoto K, Kohno K (Apr 2003). "Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression". Biochem J. 371 (Pt 2): 301–10. doi:10.1042/BJ20021646. PMC 1223307. PMID 12534345.

[entrez-7] "Entrez Gene: CEBPZ CCAAT/enhancer binding protein zeta".

[pmid11306579-8] Imbriano C, Bolognese F, Gurtner A, Piaggio G, Mantovani R (Jul 2001). "HSP-CBF is an NF-Y-dependent coactivator of the heat shock promoters CCAAT boxes". J. Biol. Chem. 276 (28): 26332–9. doi:10.1074/jbc.M101553200. hdl:11380/303761. PMID 11306579.

[autogenerated1-9] Uramoto H, Izumi H, Nagatani G, Ohmori H, Nagasue N, Ise T, Yoshida T, Yasumoto K, Kohno K (Apr 2003). "Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression". Biochem. J. 371 (Pt 2): 301–10. doi:10.1042/BJ20021646. PMC 1223307. PMID 12534345.

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CCAAT/enhancer binding protein zeta

Interactions

See also

References

Further reading

External links