ZNF43

ZNF43
Identifiers
Aliases	ZNF43, HTF6, KOX27, ZNF39L1, zinc finger protein 43
External IDs	OMIM: 603972; MGI: 3040691; HomoloGene: 128170; GeneCards: ZNF43; OMA:ZNF43 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	21,852,125 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	67,278,466 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; ganglionic eminence; ; ventricular zone; ; corpus callosum; ; testicle; ; bone marrow cells; ; gonad; ; endometrium; ; epithelium of colon; ; tonsil;
	Top expressed in
	Rostral migratory stream; ; lumbar subsegment of spinal cord; ; tail of embryo; ; genital tubercle; ; vestibular membrane of cochlear duct; ; Region I of hippocampus proper; ; ganglionic eminence; ; vas deferens; ; transitional epithelium of urinary bladder; ; embryo;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	intracellular anatomical structure; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7594
	238690
	ENSG00000198521; ENSG00000279566
	ENSMUSG00000055480
	P17038
	Q6P5C7
NM_001256648; NM_001256649; NM_001256650; NM_001256651; NM_001256653;
	NM_001256654; NM_003423
	NM_001001152
NP_001243577; NP_001243578; NP_001243579; NP_001243580; NP_001243582;
	NP_001243583; NP_003414; NP_001243577.1; NP_001243578.1; NP_001243579.1
	NP_001001152
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 43 is a protein that in humans is encoded by the ZNF43 gene.^[5]^[6]

Function

This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions.^[6]

References

^ ^a ^b ^c ENSG00000279566 GRCh38: Ensembl release 89: ENSG00000198521, ENSG00000279566 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000055480 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lovering R, Trowsdale J (Jun 1991). "A gene encoding 22 highly related zinc fingers is expressed in lymphoid cell lines". Nucleic Acids Research. 19 (11): 2921–8. doi:10.1093/nar/19.11.2921. PMC 328252. PMID 1711675.
^ ^a ^b "Entrez Gene: ZNF43 zinc finger protein 43".

External links

ZNF43+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] ENSG00000279566 GRCh38: Ensembl release 89: ENSG00000198521, ENSG00000279566 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000055480 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1711675-5] Lovering R, Trowsdale J (Jun 1991). "A gene encoding 22 highly related zinc fingers is expressed in lymphoid cell lines". Nucleic Acids Research. 19 (11): 2921–8. doi:10.1093/nar/19.11.2921. PMC 328252. PMID 1711675.

[entrez-6] "Entrez Gene: ZNF43 zinc finger protein 43".

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ZNF43

Function

See also

References

Further reading

External links