UDP-xylose and UDP-N-acetylglucosamine transporter

SLC35B4
Identifiers
Aliases	SLC35B4, YEA, YEA4, solute carrier family 35 member B4
External IDs	OMIM: 610923; MGI: 1931249; HomoloGene: 5799; GeneCards: SLC35B4; OMA:SLC35B4 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	134,316,930 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	34,154,046 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; middle temporal gyrus; ; Brodmann area 23; ; endothelial cell; ; placenta; ; retinal pigment epithelium; ; gonad; ; tibia; ; lateral nuclear group of thalamus; ; superior frontal gyrus;
	Top expressed in
	otic vesicle; ; right kidney; ; saccule; ; otic placode; ; zygote; ; proximal tubule; ; yolk sac; ; human kidney; ; secondary oocyte; ; superior frontal gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; UDP-xylose transmembrane transporter activity; GDP-fucose transmembrane transporter activity; UDP-N-acetylglucosamine transmembrane transporter activity; 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity; transmembrane transporter activity;
Cellular component	integral component of membrane; endoplasmic reticulum; membrane; integral component of Golgi membrane; integral component of endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane;
Biological process	UDP-xylose transmembrane transport; regulation of gluconeogenesis; carbohydrate transport; transmembrane transport; GDP-fucose transmembrane transport; UDP-N-acetylglucosamine transmembrane transport; 3'-phospho-5'-adenylyl sulfate transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	84912
	58246
	ENSG00000205060
	ENSMUSG00000018999
	Q969S0
	Q8CIA5
	NM_032826
	NM_021435
	NP_116215
	NP_067410
	Wikidata
View/Edit Human	View/Edit Mouse

UDP-xylose and UDP-N-acetylglucosamine transporter is a protein that in humans is encoded by the SLC35B4 gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000205060 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000018999 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: SLC35B4 solute carrier family 35, member B4".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ashikov A, Routier F, Fuhlrott J, et al. (2005). "The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine". J. Biol. Chem. 280 (29): 27230–5. doi:10.1074/jbc.M504783200. PMID 15911612.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
Kobayashi T, Sleeman JE, Coughtrie MW, Burchell B (2006). "Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family". Biochem. J. 400 (2): 281–9. doi:10.1042/BJ20060429. PMC 1652819. PMID 16965264.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000205060 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000018999 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SLC35B4 solute carrier family 35, member B4".

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UDP-xylose and UDP-N-acetylglucosamine transporter

See also

References

Further reading