Thienobenzodiazepine

Not to be confused with thienodiazepine or thienotriazolodiazepine.

Thienobenzodiazepine is a heterocyclic compound containing a diazepine ring fused to a thiophene ring and a benzene ring. Thienobenzodiazepine forms the central core of pharmaceutical drugs including atypical antipsychotic olanzapine (Zyprexa) and antimuscarinic telenzepine. Thienobenzodiazepines act relatively selectively at the α2 subunit of the GABAA receptor.[1]

References

  1. ^ a b Bymaster, Frank P; Calligaro, David O; Falcone, Julie F; Marsh, Richard D; Moore, Nicholas A; Tye, Nicholas C; Seeman, Philip; Wong, David T (February 1996). "Radioreceptor Binding Profile of the Atypical Antipsychotic Olanzapine". Neuropsychopharmacology. 4 (2): 87–96. doi:10.1016/0893-133X(94)00129-N. PMID 8822531 – via PubMed.


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