Spen

Spen may refer to:

• SPEN, human gene
• Spen, West Yorkshire, a location in England
• River Spen, river in West Yorkshire, England, the United Kingdom
• SS Spen, British steamship built in 1908
• SP Energy Networks, the energy networks arm of Scottish Power

• Spen King (1925–2010), British automobile designer
• Spen Whittaker (1871–1910), English football manager

• S Pen, stylus pen for Samsung smartphones