Slp adaptor and csk interacting membrane protein

SCIMP
Identifiers
AliasesSCIMP, C17orf87, UNQ5783, SLP adaptor and CSK interacting membrane protein
External IDsOMIM: 614406; MGI: 3610314; HomoloGene: 52602; GeneCards: SCIMP; OMA:SCIMP - orthologs
Orthologs
SpeciesHumanMouse
Entrez

388325

327957

Ensembl

ENSG00000161929

ENSMUSG00000057135

UniProt

Q6UWF3

Q3UU41

RefSeq (mRNA)

NM_001271842
NM_207103
NM_001319190

NM_001045526

RefSeq (protein)

NP_001258771
NP_001306119
NP_996986

NP_001038991

Location (UCSC)Chr 17: 5.21 – 5.23 MbChr 11: 70.68 – 70.7 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SLP adaptor and CSK interacting membrane protein is a protein encoded by the SCIMP gene in humans [5]

Function

This gene encodes a transmembrane adaptor protein that is expressed in antigen-presenting cells and localizes to the immunologic synapse. The encoded protein is involved in major histocompatibility complex class II signal transduction and immune synapse formation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012].

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000161929 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000057135 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: SLP adaptor and CSK interacting membrane protein". Retrieved 2018-05-24.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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