SiPhox Health

SiPhox Health is an American health technology company that develops at-home blood testing solutions and digital health services. Founded in 2020 and headquartered in Burlington, Massachusetts, the company offers mail-in blood testing kits and is developing a countertop diagnostic device using silicon photonics technology for instant blood analysis.[1]

History

SiPhox Health was founded in 2020 by Diedrik Vermeulen and Michael Dubrovsky, who met at the Massachusetts Institute of Technology.[2] Vermeulen, a photonics engineer, and Dubrovsky, a materials scientist, began collaborating on a miniaturized optical sensing system based on silicon photonics. Initially exploring infectious disease applications during the COVID-19 pandemic, the team shifted focus to blood-based diagnostics for chronic conditions. The company participated in Y Combinator's Summer 2020 batch and launched initial prototypes of its lab-on-a-chip technology. By 2023, SiPhox introduced a mail-in blood testing service for consumers.[3]

In July 2023, the company raised $27 million in funding led by Intel Capital, Khosla Ventures, and Y Combinator.[4][5]

Research and regulation

The company's testing is conducted through CLIA/CAP accredited laboratories with FDA-registered components. Vermeulen has published 108 peer-reviewed publications and holds 28 patents in photonics.[6]

Reception and impact

In February 2025, The Boston Globe featured SiPhox in a story highlighting the company's approach to home blood testing.[7] The company has been positioned as learning from the failures of Theranos, with established laboratory partnerships and transparent validation processes. A notable case involved Colin Godby, CEO of Dust Moto, who discovered he had hereditary hemochromatosis through SiPhox testing after years of routine medical visits failed to test his iron levels. His dangerously high ferritin levels, if left undetected, could have led to liver or heart failure within 10–15 years.

See also

References

  1. ^ "Do-it-yourself home blood tests may be available next year from this Burlington company". BostonGlobe.com. Retrieved 2025-07-04.
  2. ^ "SiPhox brings lab testing home". MIT News. November 14, 2024.
  3. ^ "SiPhox Health lands $27M for silicon photonics test kits". Optics.org. Retrieved 2025-06-26.
  4. ^ "Intel Capital and Khosla Ventures Lead $27M Investment in SiPhox Health to Transform Health Testing". Business Wire. July 19, 2023.
  5. ^ "Intel, Khosla back $27M round for SiPhox Health's at-home blood test". TechCrunch. July 19, 2023.
  6. ^ "Silicon photonics for health monitoring". IEEE Xplore: 1–2. 2023. doi:10.1109/SiPhotonics55903.2023.10141929.
  7. ^ "SiPhox brings blood tests home". The Boston Globe. February 11, 2025.
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