S-350 (drug)

S-350
Identifiers
  • 3-[4-[2-[(4-fluorophenyl)-phenylmethoxy]ethyl]piperazin-1-yl]propanoic acid
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC22H27FN2O3
Molar mass386.467 g·mol−1
3D model (JSmol)
  • C1CN(CCN1CCC(=O)O)CCOC(C2=CC=CC=C2)C3=CC=C(C=C3)F
  • InChI=1S/C22H27FN2O3/c23-20-8-6-19(7-9-20)22(18-4-2-1-3-5-18)28-17-16-25-14-12-24(13-15-25)11-10-21(26)27/h1-9,22H,10-17H2,(H,26,27)
  • Key:YHKKVXZGTGCXTP-UHFFFAOYSA-N

S-350 is a psychostimulating (psychoanaleptic) piperazine. The pharmacological outcome is based on the structure of antihistamines related to diphenhydramine.[1][2] S-350 is of historic significance since it can be viewed as the logical progenitor or harbinger to vanoxerine and other GBR agents that were discovered in short succession. The drug comes in 16 millimeter pills, and can help treat substance abuse in individuals.[3]

See also

References

  1. ^ Buzas A, Champagnac A, Dehnel A, Lavielle G, Pommier M (February 1980). "Synthesis and psychoanaleptic properties of new compounds structurally related to diphenhydramine". Journal of Medicinal Chemistry. 23 (2): 149–53. doi:10.1021/jm00176a009. PMID 6102153.
  2. ^ US 4096259, Buzas A, Melon JM, "Non-amphetaminic psychostimulating compositions of 1,4-disubstituted piperazines", issued 20 June 1978 
  3. ^ Selected Mental Health Audiovisuals. Maryland: National Institute of Mental Health. 1975. p. 10. OCLC 911439427.
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