RUNDC3A

RUNDC3A
Identifiers
Aliases	RUNDC3A, RAP2IP, RPIP-8, RPIP8, RUN domain containing 3A
External IDs	OMIM: 605448; MGI: 1858752; HomoloGene: 4871; GeneCards: RUNDC3A; OMA:RUNDC3A - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	44,318,670 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	102,293,381 bp
RNA expression pattern
	Top expressed in
	right frontal lobe; ; right hemisphere of cerebellum; ; cingulate gyrus; ; anterior cingulate cortex; ; prefrontal cortex; ; Brodmann area 9; ; amygdala; ; nucleus accumbens; ; caudate nucleus; ; hippocampus proper;
	Top expressed in
	neural layer of retina; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; cerebellar cortex; ; entorhinal cortex; ; perirhinal cortex; ; CA3 field; ; primary motor cortex; ; lobe of cerebellum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; guanylate cyclase activator activity; GTPase regulator activity; peptide hormone receptor binding;
Cellular component	cytosol; plasma membrane;
Biological process	small GTPase mediated signal transduction; positive regulation of guanylate cyclase activity; regulation of catalytic activity; positive regulation of cGMP-mediated signaling;
	Sources:Amigo / QuickGO
Orthologs
	10900
	51799
	ENSG00000108309
	ENSMUSG00000006575
	Q59EK9
	O08576
	NM_001144825; NM_001144826; NM_006695
	NM_001252347; NM_016759; NM_001362803; NM_001362804
	NP_001138297; NP_001138298; NP_006686
	NP_001239276; NP_058039; NP_001349732; NP_001349733
	Wikidata
View/Edit Human	View/Edit Mouse

RUN domain-containing protein 3A is a protein that in humans is encoded by the RUNDC3A gene.^[5]^[6]

Interactions

RUNDC3A has been shown to interact with RAP2A.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000108309 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000006575 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Janoueix-Lerosey I, Pasheva E, de Tand MF, Tavitian A, de Gunzburg J (Apr 1998). "Identification of a specific effector of the small GTP-binding protein Rap2". Eur. J. Biochem. 252 (2): 290–8. doi:10.1046/j.1432-1327.1998.2520290.x. PMID 9523700.
^ "Entrez Gene: RPIP8 RaP2 interacting protein 8".

Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000108309 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000006575 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9523700-5] Janoueix-Lerosey I, Pasheva E, de Tand MF, Tavitian A, de Gunzburg J (Apr 1998). "Identification of a specific effector of the small GTP-binding protein Rap2". Eur. J. Biochem. 252 (2): 290–8. doi:10.1046/j.1432-1327.1998.2520290.x. PMID 9523700.

[entrez-6] "Entrez Gene: RPIP8 RaP2 interacting protein 8".

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[3]

[4]

[5]

[6]

RUNDC3A

Interactions

See also

References

Further reading