Phenopicolinic acid
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Names
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Preferred IUPAC name
5-[(4-Hydroxyphenyl)methyl]pyridine-2-carboxylic acid
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Identifiers
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ChemSpider
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UNII
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InChI=1S/C13H11NO3/c15-11-4-1-9(2-5-11)7-10-3-6-12(13(16)17)14-8-10/h1-6,8,15H,7H2,(H,16,17) Key: SJBFZHNCSGBLEK-UHFFFAOYSA-N InChI=1/C13H11NO3/c15-11-4-1-9(2-5-11)7-10-3-6-12(13(16)17)14-8-10/h1-6,8,15H,7H2,(H,16,17) Key: SJBFZHNCSGBLEK-UHFFFAOYAB
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C1=CC(=CC=C1CC2=CN=C(C=C2)C(=O)O)O
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Properties
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C13H11NO3
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Molar mass
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229.235 g·mol−1
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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Phenopicolinic acid is a dopamine beta hydroxylase inhibitor.[1]
References
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Non-specific | AAADTooltip Aromatic L-amino acid decarboxylase | |
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MAOTooltip Monoamine oxidase | |
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Phenethylamines (dopamine, epinephrine, norepinephrine) | PAHTooltip Phenylalanine hydroxylase | |
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THTooltip Tyrosine hydroxylase | |
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DBHTooltip Dopamine beta-hydroxylase | |
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PNMTTooltip Phenylethanolamine N-methyltransferase |
- Inhibitors: CGS-19281A
- SKF-64139
- SKF-7698
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COMTTooltip Catechol-O-methyl transferase | |
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Tryptamines (serotonin, melatonin) | TPHTooltip Tryptophan hydroxylase | |
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AANATTooltip Serotonin N-acetyl transferase | |
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ASMTTooltip Acetylserotonin O-methyltransferase | |
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Histamine | HDCTooltip Histidine decarboxylase | |
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HNMTTooltip Histamine N-methyltransferase |
- Substrates→Products: Histamine→N-Methylhistamine
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DAOTooltip Diamine oxidase |
- Substrates→Products: Histamine→Imidazole acetic acid
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See also: Receptor/signaling modulators • Adrenergics • Dopaminergics • Melatonergics • Serotonergics • Monoamine reuptake inhibitors • Monoamine releasing agents • Monoamine neurotoxins |