LAPTM4A

LAPTM4A
Identifiers
Aliases	LAPTM4A, HUMORF13, LAPTM4, MBNT, Mtrp, lysosomal protein transmembrane 4 alpha
External IDs	MGI: 108017; HomoloGene: 7427; GeneCards: LAPTM4A; OMA:LAPTM4A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	20,051,628 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	8,988,742 bp
RNA expression pattern
	Top expressed in
	seminal vesicula; ; skin of hip; ; germinal epithelium; ; synovial joint; ; urethra; ; caput epididymis; ; Epithelium of choroid plexus; ; mucosa of paranasal sinus; ; tail of epididymis; ; superficial temporal artery;
	Top expressed in
	corneal stroma; ; calvaria; ; choroid plexus of fourth ventricle; ; molar; ; seminal vesicula; ; extensor digitorum longus muscle; ; extraocular muscle; ; right lung; ; lactiferous gland; ; umbilical cord;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	endomembrane system; integral component of membrane; Golgi apparatus; membrane; lysosomal membrane; late endosome membrane;
Biological process	transport;
	Sources:Amigo / QuickGO
Orthologs
	9741
	17775
	ENSG00000068697
	ENSMUSG00000020585
	Q15012
	Q60961
	NM_014713
	NM_008640
	NP_055528
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Lysosomal protein transmembrane 4 alpha is a protein that in humans is encoded by the LAPTM4A gene. ^[5]

Function

This gene encodes a protein that has four predicted transmembrane domains. The function of this gene has not yet been determined; however, studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000068697 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020585 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Lysosomal protein transmembrane 4 alpha". Retrieved 2017-07-03.

Function

References

Further reading