Frank Henderson

Frank Henderson may refer to:

• Frank Henderson (cricketer) (1908–1954), Australian cricketer
• Frank Henderson (poker player) (born 1931), American poker player
• Frank Henderson (public servant) (1911–1969), Australian public servant
• Frank Henderson (Scottish politician) (1836–1889), Scottish Liberal politician
• Frank Henderson (South Dakota politician) (1928–2012), American politician from South Dakota
• Frank Henderson (Idaho politician) (1922–2015), Republican Idaho state representative
• Frank Henderson (footballer) (1900–1966), English football left half
• Frank Henderson (Irish revolutionary) (1886–1959), captain in the Irish Volunteers