Extracellular matrix protein 2

ECM2
Identifiers
Aliases	ECM2, extracellular matrix protein 2
External IDs	OMIM: 603479; MGI: 3039578; HomoloGene: 1064; GeneCards: ECM2; OMA:ECM2 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	92,536,655 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	49,686,265 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; synovial joint; ; right coronary artery; ; parietal pleura; ; skin of hip; ; tibia; ; vena cava; ; germinal epithelium; ; Descending thoracic aorta; ; ascending aorta;
	Top expressed in
	esophagus; ; aorta; ; muscle of thigh; ; ascending aorta; ; lumbar spinal ganglion; ; lip; ; extraocular muscle; ; aortic valve; ; interventricular septum; ; soleus muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	collagen V binding; integrin binding; heparin binding; collagen binding;
Cellular component	extracellular region; interstitial matrix; extracellular space; extracellular matrix;
Biological process	cell-matrix adhesion; extracellular matrix organization; axonogenesis; positive regulation of cell-substrate adhesion;
	Sources:Amigo / QuickGO
Orthologs
	1842
	407800
	ENSG00000106823
	ENSMUSG00000043631
	O94769
	Q5FW85
	NM_001393; NM_001197295; NM_001197296
	NM_001012324
	NP_001184224; NP_001184225; NP_001384
	NP_001012324
	Wikidata
View/Edit Human	View/Edit Mouse

Extracellular matrix protein 2 is a protein that in humans is encoded by the ECM2 gene.^[5]^[6]

ECM2 encodes extracellular matrix protein 2, so named because it shares extensive similarity with known extracellular matrix proteins.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000106823 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000043631 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nishiu J, Tanaka T, Nakamura Y (Dec 1998). "Identification of a novel gene (ECM2) encoding a putative extracellular matrix protein expressed predominantly in adipose and female-specific tissues and its chromosomal localization to 9q22.3". Genomics. 52 (3): 378–81. doi:10.1006/geno.1998.5455. PMID 9790758.
^ ^a ^b "Entrez Gene: ECM2 extracellular matrix protein 2, female organ and adipocyte specific".

Oritani K, Kanakura Y, Aoyama K, et al. (1997). "Matrix glycoprotein SC1/ECM2 augments B lymphopoiesis". Blood. 90 (9): 3404–13. doi:10.1182/blood.V90.9.3404. PMID 9345023.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000106823 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000043631 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9790758-5] Nishiu J, Tanaka T, Nakamura Y (Dec 1998). "Identification of a novel gene (ECM2) encoding a putative extracellular matrix protein expressed predominantly in adipose and female-specific tissues and its chromosomal localization to 9q22.3". Genomics. 52 (3): 378–81. doi:10.1006/geno.1998.5455. PMID 9790758.

[entrez-6] "Entrez Gene: ECM2 extracellular matrix protein 2, female organ and adipocyte specific".

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References

Further reading