Carbazole alkaloids

The carbazole alkaloids are natural products of the indole alkaloid type, derived from carbazole.[1]

Occurrence

Carbazole alkaloids with unsubstituted benzene rings occur rarely. Olivacin has been found in the bark of Aspidosperma olivaceum and ellipticin in Ochrosia elliptica.[2] Some carbazole alkaloids, especially glybomin B, have been isolated from Glycosmis pentaphylla.[3]

Representatives

Representatives include, among others, glycozoline, olivacine and ellipticin[2] and further glybomine B.[3]

  • Glycozoline
  • Olivacine
  • Ellipticin
  • Glybomine B

Properties

Carbazole alkaloids have cytotoxic and antifungal properties. Furthermore, they have detrimental effects against HIV viruses and tumor cells.[3] Olivacin has fluorescent properties.[2]

References

  1. ^ Entry on carbazole alkaloids. In: Römpp Online. Georg Thieme Verlag, accessed May 31, 2020.
  2. ^ a b c Eberhard Breitmaier (1997), Alkaloide, Wiesbaden: Springer Fachmedien, p. 49, ISBN 978-3-519-03542-8
  3. ^ a b c G. Yang, Y. Wu, Y. Chen (2012), "Alkaloids from the Stems of Glycosmis pentaphylla", Helvetica Chimica Acta, vol. 95, no. 8, pp. 1449–1454, doi:10.1002/hlca.201200027{{citation}}: CS1 maint: multiple names: authors list (link)
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