CD300C

CD300C
Identifiers
AliasesCD300C, CLM-6, CMRF-35, CMRF-35A, CMRF35, CMRF35-A1, CMRF35A, CMRF35A1, IGSF16, LIR, CD300c molecule
External IDsOMIM: 606786; MGI: 2153249; HomoloGene: 74580; GeneCards: CD300C; OMA:CD300C - orthologs
Orthologs
SpeciesHumanMouse
Entrez

10871

140497

Ensembl

ENSG00000167850

ENSMUSG00000044811

UniProt

Q08708

Q7TSN2

RefSeq (mRNA)

NM_006678

NM_134158

RefSeq (protein)

NP_006669

NP_598919

Location (UCSC)Chr 17: 74.54 – 74.55 MbChr 11: 114.89 – 114.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CMRF35-like molecule 6 (CLM-6) also known as CD300 antigen-like family member C (CD300c) is a protein that in humans is encoded by the CD300C gene.[5][6][7]

The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes.[7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000167850 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044811 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Jackson DG, Hart DN, Starling G, Bell JI (Jun 1992). "Molecular cloning of a novel member of the immunoglobulin gene superfamily homologous to the polymeric immunoglobulin receptor". Eur J Immunol. 22 (5): 1157–63. doi:10.1002/eji.1830220508. PMID 1349532. S2CID 23437463.
  6. ^ Clark GJ, Green BJ, Hart DN (Aug 2000). "The CMRF-35H gene structure predicts for an independently expressed member of an ITIM/ITAM pair of molecules localized to human chromosome 17". Tissue Antigens. 55 (2): 101–9. doi:10.1034/j.1399-0039.2000.550201.x. PMID 10746781.
  7. ^ a b "Entrez Gene: CD300C CD300c molecule".

Further reading

  • Clark GJ, Fitzpatrick S, Kuo B, Modra C, Jamriska L, Hart DN (2002). "CMRF-35A, CMRF-35H: potential new CD". J. Biol. Regul. Homeost. Agents. 16 (3): 233–5. PMID 12456026.
  • Cannon JP, Haire RN, Litman GW (December 2002). "Identification of diversified genes that contain immunoglobulin-like variable regions in a protochordate". Nat. Immunol. 3 (12): 1200–7. doi:10.1038/ni849. PMID 12415263. S2CID 19367972.
  • Clark GJ, Cooper B, Fitzpatrick S, Green BJ, Hart DN (May 2001). "The gene encoding the immunoregulatory signaling molecule CMRF-35A localized to human chromosome 17 in close proximity to other members of the CMRF-35 family". Tissue Antigens. 57 (5): 415–23. doi:10.1034/j.1399-0039.2001.057005415.x. PMID 11556966.


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