Alphapolyomavirus
| Alphapolyomavirus | |
|---|---|
| Alphapolyomavirus model with a non-enveloped capsid and a T = 7d icosahedral symmetry at a 50 nm diameter scale | |
| Virus classification | |
| (unranked): | Virus |
| Realm: | Monodnaviria |
| Kingdom: | Shotokuvirae |
| Phylum: | Cossaviricota |
| Class: | Papovaviricetes |
| Order: | Sepolyvirales |
| Family: | Polyomaviridae |
| Genus: | Alphapolyomavirus |
Alphapolyomavirus is one of eight genera of non-enveloped dsDNA viruses in the Polyomaviridae family.[1][2] Member viruses primarily infect humans and other mammals.[3] Transmission of the virus in humans is primarily spread via direct contact with parents or other high-contact individuals as children.[4][5]
The primary alphapolyomavirus that is of clinical significance to humans is Merkel cell polyomavirus (Human polyomavirus 5, MCV, or MCPyV). The apparent oncogenicity of MCPyV[6] similar to other cancer-causing viruses such as HPV, Epstein–Barr virus, and Hepatitis C virus[7] is a main area of research for the scientific community.
Species
The genus contains the following species, listed by scientific name and followed by the exemplar virus of the species:[8][9]
- Alphapolyomavirus acelebensis, Bat polyomavirus 5b2
- Alphapolyomavirus aflavicollis, Apodemus flavicollis polyomavirus 1
- Alphapolyomavirus apaniscus, Ateles paniscus polyomavirus 1
- Alphapolyomavirus callosciuri, Callosciurus erythraeus polyomavirus 1
- Alphapolyomavirus cardiodermae, Cardioderma polyomavirus
- Alphapolyomavirus carolliae, Bat polyomavirus 4b
- Alphapolyomavirus castoris, Castor fiber polyomavirus 1
- Alphapolyomavirus chlopygerythrus, Vervet monkey polyomavirus 1
- Alphapolyomavirus dobsoniae, Bat polyomavirus 5a
- Alphapolyomavirus eidoli, Eidolon polyomavirus 1
- Alphapolyomavirus epserotini, Eptesicus serotinus polyomavirus 1
- Alphapolyomavirus gorillae, Gorilla gorilla gorilla polyomavirus 1
- Alphapolyomavirus macacae, Macaca fascicularis polyomavirus 1
- Alphapolyomavirus mauratus, Hamster polyomavirus
- Alphapolyomavirus mischreibersii, Miniopterus schreibersii polyomavirus 1
- Alphapolyomavirus molossi, Bat polyomavirus 3b
- Alphapolyomavirus muris, Mouse polyomavirus
- Alphapolyomavirus myodaubentonii, Myotis daubentonii polyomavirus 2
- Alphapolyomavirus nonihominis, Human polyomavirus 9
- Alphapolyomavirus octihominis, Trichodysplasia spinulosa-associated polyomavirus
- Alphapolyomavirus omartiensseni, Otomops polyomavirus 1
- Alphapolyomavirus pacynocephalus, Yellow baboon polyomavirus 1
- Alphapolyomavirus panos, Chimpanzee polyomavirus
- Alphapolyomavirus philantombae, Philantomba monticola polyomavirus 1
- Alphapolyomavirus pibadius, Piliocolobus badius polyomavirus 2
- Alphapolyomavirus pirufomitratus, Piliocolobus rufomitratus polyomavirus 1
- Alphapolyomavirus ponabelii, Sumatran orang-utan polyomavirus
- Alphapolyomavirus ponpygmaeus, Bornean orang-utan polyomavirus
- Alphapolyomavirus procyonis, Raccoon polyomavirus
- Alphapolyomavirus ptevampyrus, Bat polyomavirus 5b1
- Alphapolyomavirus quardecihominis, LI polyomavirus
- Alphapolyomavirus quartipanos, Pan troglodytes verus polyomavirus 3
- Alphapolyomavirus quintihominis, Merkel cell polyomavirus
- Alphapolyomavirus quintipanos, Pan troglodytes verus polyomavirus 4
- Alphapolyomavirus ranorvegicus, Rattus norvegicus polyomavirus 1
- Alphapolyomavirus saraneus, Sorex araneus polyomavirus 1
- Alphapolyomavirus secarplanirostris, Bat polyomavirus 3a
- Alphapolyomavirus secomartiensseni, Otomops polyomavirus 2
- Alphapolyomavirus secumastomysis, Mastomys natalensis polyomavirus 2
- Alphapolyomavirus secumischreibersii, Miniopterus schreibersii polyomavirus 2
- Alphapolyomavirus secupanos, Pan troglodytes verus polyomavirus 1a
- Alphapolyomavirus septipanos, Pan troglodytes schweinfurthii polyomavirus 2
- Alphapolyomavirus sextipanos, Pan troglodytes verus polyomavirus 5
- Alphapolyomavirus socoronatus, Sorex coronatus polyomavirus 1
- Alphapolyomavirus sominutus, Sorex minutus polyomavirus 1
- Alphapolyomavirus sturnirae, Bat polyomavirus 3a-B0454
- Alphapolyomavirus suis, Sus scrofa polyomavirus 1
- Alphapolyomavirus terdecihominis, New Jersey polyomavirus
- Alphapolyomavirus tertarplanisrostris, Bat polyomavirus 4a
- Alphapolyomavirus tertichlopygerythrus, Vervet monkey polyomavirus 3
- Alphapolyomavirus tertimastomysis, Mastomys natalensis polyomavirus 3
- Alphapolyomavirus tertipanos, Pan troglodytes verus polyomavirus 2a
- Alphapolyomavirus tubelangeri, Tupaia belangeri polyomavirus
- Alphapolyomavirus tuglis, Tupaia glis polyomavirus 1
References
- ^ taxonomy. "Taxonomy browser (Polyomaviridae)". www.ncbi.nlm.nih.gov. Retrieved 2024-03-19.
- ^ "Alphapolyomavirus ~ ViralZone". viralzone.expasy.org. Retrieved 2024-03-19.
- ^ "Genus: Alphapolyomavirus | ICTV". ictv.global. Retrieved 2024-03-19.
- ^ Kunitake, T; Kitamura, T; Guo, J; Taguchi, F; Kawabe, K; Yogo, Y (Jun 1995). "Parent-to-child transmission is relatively common in the spread of the human polyomavirus JC virus". Journal of Clinical Microbiology. 33 (6): 1448–1451. doi:10.1128/jcm.33.6.1448-1451.1995. ISSN 0095-1137. PMC 228193. PMID 7650165.
- ^ Boothpur, Raghavender; Brennan, Daniel C. (Apr 2010). "Human Polyoma Viruses and Disease with Emphasis on Clinical BK and JC". Journal of Clinical Virology. 47 (4): 306–312. doi:10.1016/j.jcv.2009.12.006. ISSN 1386-6532. PMC 3774018. PMID 20060360.
- ^ Spurgeon, Megan E.; Lambert, Paul F. (2013-01-05). "Merkel Cell Polyomavirus: A Newly Discovered Human Virus with Oncogenic Potential". Virology. 435 (1): 118–130. doi:10.1016/j.virol.2012.09.029. ISSN 0042-6822. PMC 3522868. PMID 23217622.
- ^ "Gale – Product Login". galeapps.gale.com. Retrieved 2024-03-19.
- ^ "Virus Taxonomy: 2024 Release". International Committee on Taxonomy of Viruses. Retrieved 25 March 2025.
- ^ "Species List: Polyomaviridae". International Committee on Taxonomy of Viruses. Retrieved 25 March 2025.