2007–08 Maltese First Division knock-out

The 2007–08 Maltese First Division Knock-Out (known as Maltco Lotteries First Division Knock-Out due to sponsorship reasons) was a knockout tournament for Maltese football clubs playing in the First Division. The winners were Dingli Swallows and the runners-up were Vittoriosa Stars.

The competition began on 18 November 2007 and ended on 1 June 2008 with the final.

The competition began with a preliminary round. Four teams played in the preliminary round. The two winners of the preliminary round advanced to the quarter-finals with the rest teams from the First Division. The four winners from the quarter-finals, which were Dingli Swallows, Mosta, Tarxien Rainbows and Vittoriosa Stars, advanced to the semi-finals.

• 2007–08 Maltese First Division